S100A4 and cancer: Based on the analysis results of the SingleR package (Figures 8(d) and 8(h)), we speculated that cluster 10 and cluster 7 from patient A, the epithelial cell clusters most obviously expressing TM4SF1 and S100A4, respectively, were cancer cells, while the cancer cell cluster in patient B was cluster 3, which expressed TM4SF1 most obviously [19].