TDRD7 and cataract: Additionally, Hsf4, Tdrd7, gap junction protein epsilon 1 (Gje1), beaded filament structural protein 2 (Bfsp2), and lens intrinsic membrane protein 2 (Lim2) which are also significantly reduced in the SCR lens (<0.5-fold) were linked to human or animal cataracts (Supplement 1) [27–33].