Candidate target genes of upregulated DE-miRNAs were significantly enriched in Prion diseases, axon guidance, ABC transporters, human T-cell leukemia virus 1 infection, viral myocarditis, pathways in cancer, colorectal cancer, MAPK signaling pathway, rheumatoid arthritis, and the AGE-RAGE signaling pathway in diabetic complications (Figures 6(a) and 6(b)). This evidence concerns the gene RENBP and prion disease.