According to the sample size (less than 90 or more), tumor type (digestive tumors or others), cutoff value (mean, median, or 2-ΔΔCt), and follow-up time (less than 60 or more), we conducted stratified analyses to confirm the relationship between SPRY4-IT1 expression and OS in different subgroups. Here, HAUS3 is linked to digestive system neoplasm.