In a study designed to test the reproducibility of the assessment of PD-L1 expression (PD-L1 22C3) in NSCLC tissue samples by 10 pathologists, the overall percent agreement (OPA) was approximately 90% and 80% for intraobserver and interobserver reproducibility, respectively, indicating that pathologists reported good reproducibility [25]. Here, CD274 is linked to non-small cell lung carcinoma.