Due to its muramidase activity, lysozyme has long been known to exert its antimicrobial action by specially hydrolyzing the 1,4-D-linkage between N-acetylmuramic acid and N-acetyl-D-glucosamine of cell wall peptidoglycan which is the major component of the gram-positive bacterial cell wall [86], hence inducing bacterial lysis and providing some protection against bacterial infection. Here, LYZ is linked to bacterial infectious disease.