Gonzalez-Hormazabal et al. used a combined attribute network implemented in multifactor dimensionality reduction software to analyze the gene-gene interactions between IL-8-251 A>T and IL-32 rs28372698 T/A, and their results showed that the homozygote for both IL-8-251 T and IL-32 rs28372698 T alleles presents a 2.63-fold risk in the developing gastric cancer (29). Here, CXCL8 is linked to gastric cancer.