Soler et al. designed a novel differential diagnostic approach merging analysis of secretion of two MDSC biomarkers; traditional HLA-DR as well as novel vascular noninflammatory molecule 2 (VNN2+) secretion on CD14+ monocytes was obtained from PBMC of GBM and/or radiation necrosis (RN) patients [126]. The gene discussed is CD14; the disease is glioblastoma.