ABCC3 and Jaundice: Taken the present information together, Yinzhihuang granules have the following four mechanisms to remove jaundice, protect liver, and reduce enzyme activities: (1) preventing liver injury by antagonizing the serum ALT and AST activities induced by CCl4; (2) anticholestasis, promoting bilirubin excretion and clearance; (3) upregulating the expression of Mrp2 and Mrp3, reducing the accumulation of bilirubin; and (4) promoting the proliferation, repair, and regeneration of hepatocytes, thereby protecting the liver.