LASSO regression identified a combination of 3 biomarkers post operatively to stratify risk of AKI, namely H-FABP, sTNFR1 and MK (Table 2) (H-FABP, sTNFR1 and MK combined sensitivity 80.5%; specificity 86.0%; AUROC 0.885 (CI 0.825—0.944) (Fig. 3A,B)). This evidence concerns the gene MDK and acute kidney injury.