BRAF and Miyoshi myopathy: As shown in Table 2, loss-of-function (LoF) and missense mutations were significantly more frequent (P < 0.001) for partner genes with BRAF in SCS interaction sets in the multidrug combined MM cell lines, and the copy number variation (CNV) deletion frequency tended to be higher, but the difference was not statistically significant (P < 0.1).