Finally, N-terminal cleavage of GPR37L1-eYFP was not unique to HEK293 cells, as the same GPR37L1-eYFP processing and response to deglycosylation was also observed in the more physiologically-relevant human glioblastoma U87 MG cell line transiently transfected with either wild-type or Δ122 GPR37L1-eYFP (Fig. 1f). Here, GPR37L1 is linked to glioblastoma.