To investigate the effect of tyrosine phosphorylation of lipin-1 on mouse mammary tumour, we first generated MMTV-Long Terminal Repeat (MMTV/LTR) promoter-driven adeno-associated viruses (AAV) carrying WT-lipin-1, 3YF-lipin-1 or GFP as a control, referred to as AAV-WT-lipin-1, AAV-3YF-lipin-1 and AAV-ctrl. This evidence concerns the gene LPIN1 and breast cancer.