The levels of IFN-λ1 mRNA (Fig. 6C), IFN-λ2/3 mRNA (Fig. 6D), and IFN-λ1 protein (Fig. 6E) were induced in HT29 cells upon CVB3 and PV1 infections, while the inductions of type III IFNs induced by CVB3 and PV1 were suppressed by shTLR3 (Fig. 6C to E). The gene discussed is PLVAP; the disease is infection.