PLK3 and age-related macular degeneration: The HGT-derived Calvin cycle-related gene cluster prk-rbcLS-cbbX was present in clades II and IV of Acidiphilium (see Fig. S10 to S14 at https://doi.org/10.6084/m9.figshare.12892016.v1), which might help Acidiphilium overcome oligotrophic AMD conditions through CO2 assimilation.