PTEN and hepatocellular carcinoma: They have been reported to increase FAO in the same way as cyanidins [51], and, remarkably, to attenuate tumor growth in HCC by regulating BAX and caspase-3 for apoptosis; several cyclin isoforms and phosphatase and tensin homolog (PTEN) for proliferation and metastasis derived from MMP-2/9 activity [56].