CREBBP and genitopatellar syndrome: There is evidence of germline mutations in several KATs (for example, KAT6A, KAT6B, CREB- binding protein (CBP) and EP300) that result in disorders, for example, Say–Barber–Biesecker–Young–Simpson (or Ohdo) syndrome [52], Genitopatellar syndrome [53,54] or Rubinstein–Taybi syndrome.