In the case of bone, the induction of autophagy by rapamycin (the pharmacological inhibition of mTOR) may function as an effective therapeutic approach for the promotion of fracture healing [63] and promoting autophagy via the 5’ AMP-activated protein kinase (AMPK)/mTOR pathway might be an effective agent for the prevention of glucocorticoid-induced osteoporosis [64]. The gene discussed is MTOR; the disease is osteoporosis.