Subanalysis performed within the asthma group (IgE > 100/ IgE < 1 00 kIU/L; sputum eosinophilia > 3%/sputum eosinophilia < 3%) did not show any significant differences in terms of tested cytokine concentrations at protein and mRNA level. The gene discussed is IGHE; the disease is Increased total eosinophil count.