Furthermore, monocytes and macrophages in IgE-treated rat tumours showed enhanced intracellular TNFα and IL-10 expression, and significantly upregulated TNFα, MCP-1 and IL-10 levels in the bronchoalveolar lavage (BAL) fluid, compared with IgG- or PBS control-treated groups [12,23]. This evidence concerns the gene TNF and neoplasm.