IL18 and metabolic dysfunction-associated steatohepatitis: In order to establish whether ASC, IL-18, and Gal-3 proteins could be considered as reliable biomarkers of NASH, the area under the curve (AUC) was determined for ASC (Figure 2A), IL-18 (Figure 2B), Gal-3 (Figure 2C), and CRP (Figure 2D).