The cut-off point for ASC was 394.9 pg/mL with 81% sensitivity and 60% specificity, the IL-18 cut-off point was 269.2 pg/mL with 77% sensitivity and 60% specificity, and for Gal-3, the cut-off point was 7120 pg/mL with 75% sensitivity and 49% specificity (Table 2); thus, indicating that ASC, IL-18, and Gal-3 are reliable biomarkers of NASH. This evidence concerns the gene IL18 and metabolic dysfunction-associated steatohepatitis.