Indeed, the findings of hyperglycemia, severe insulin resistance requiring high doses of insulin to control these elevated blood glucose levels, increased ketosis and especially the hyperosmolar hyperglycemic state (nonketotic) (HHS) in older individuals suggest that COVID-19 is capable of having diabetogenic effects that exceed the well-accepted and recognized stress response associated with severe illnesses [5]. The gene discussed is INS; the disease is COVID-19.