Notably, ACE2 staining expression in adipose tissue is known to be higher than pulmonary tissue and contribute to the pre-COVID-19 MetS and T2DM chronic low-grade inflammatory state once it becomes affected as an immediate stressor and could contribute to an ongoing source of chronic inflammation (meta-inflammation) in post-COVID-19 recovery and long-term complications [2,3,4]. The gene discussed is ACE2; the disease is type 2 diabetes mellitus.