INS and Insulin resistance: Plasma insulin levels (F(2,33) = 3.7, p < 0.05: Figure 2C) and the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) (F(2,31) = 7.6, p < 0.01; Figure 2D) were affected by diet, with both HFD and CCD inducing an overall increase in these parameters, with the CCD effect on insulin being more apparent in females.