SEZ6L2 belongs to the SEZ6 family, which is composed of SEZ6, SEZ6L, and SEZ6L2 [18] and is upregulated in various cancers compared to the matched normal samples according to GEPIA2 (Gene Expression Profiling Interactive Analysis) webserver (http://gepia2.cancer-pku.cn/). The gene discussed is SEZ6L2; the disease is cancer.