ADIPOQ and autoimmune disease: The aim of this study was to investigate the role of some specific cytokines such as adiponectin and TNF-α in the pathogenesis and evolution of T1DM in children and adolescents, by searching possible correlations between laboratory values and risk of T1DM, as well as to determine whether there is a link between serum levels of certain biomarkers and Z scores for weight, height, and BMI, age at the onset of the disease, association of other autoimmune disorders and onset of complications in T1DM pediatric patients.