PNLIP and familial pancreatic carcinoma: The fGn system is postulated to enhance the activity of PTL by assisting in the drug-internalization process, enhancing the water-solubility of the drug and improving cellular drug uptake Delivery by fGn was found to enhance the anticancer/apoptotic profile of PTL when delivered to the human pancreatic cancer cell line, Panc-1, while DMAPT was not [635].