In the present study of mice subjected to the activity-based anorexia, we report that: (i) Progressive refeeding is associated with a partial restoration of body weight with a maintained altered body composition, (ii) both Gln and BCAA-supplemented refeeding fail to improve body composition and body weight, and (iii) Gln-supplemented refeeding, but not BCAA-supplemented, is associated with a mTOR-mediated increase in colonic protein synthesis. This evidence concerns the gene MTOR and Anorexia.