Recently, the expression levels of mitotic spindle genes (Aurora kinases (AURKA, AURKB, AURKC), kinesin-like protein 11 (KIF11), discs large-associated protein 5(DLGAPS5), cytoskeleton-associated protein 5 (CKAP5), monopolar spindle 1 kinase (TTK) and β-tubulins (TUBB and TUBB3), microtubule nucleation factor (TPX2), and their association with the clinicopathological characteristics were investigated in NSCLC tumor and adjacent normal lung tissues. The gene discussed is CKAP5; the disease is neoplasm.