Using bio-informatic-based enrichment analyses, Zhang’s group [17] reported that elevated mRNA of AURKA, CDC20, and TPX2 were significantly associated with poor prognosis in smoking-related lung adenocarcinoma, indicating the potential of using AURKA, CDC20, and TPX2 as biomarkers for predicting poor prognosis in smoking-related lung cancer. This evidence concerns the gene CDC20 and lung cancer.