Cumulative data from immunohistochemical analyses of NSCLC samples indicated that high AURKB expression correlated with poor prognosis [22,23,24], lymph node metastasis, poor tumor differentiation grade, histological type of NSCLC [24,43] and genetic instability [44], suggesting that AURKB may contribute to malignancy and may represent a valid target in NSCLC. Here, AURKB is linked to neoplasm.