Recently, the expression levels of mitotic spindle genes (Aurora kinases (AURKA, AURKB, AURKC), kinesin-like protein 11 (KIF11), discs large-associated protein 5(DLGAPS5), cytoskeleton-associated protein 5 (CKAP5), monopolar spindle 1 kinase (TTK) and β-tubulins (TUBB and TUBB3), microtubule nucleation factor (TPX2), and their association with the clinicopathological characteristics were investigated in NSCLC tumor and adjacent normal lung tissues. This evidence concerns the gene CKAP5 and non-small cell lung carcinoma.