When we searched the literature for information about the genes corresponding to the six CpG sites in our prognostic model (BDH1, SYTL1, SATB2, WDR20, DMC1 and ZNF35), we found that ZNF35 and SATB2 have already been established as reliable prognostic marker genes for COAD. The gene discussed is ZNF35; the disease is colon adenocarcinoma.