DAPK1 and nonpapillary renal cell carcinoma: As shown in Table 2, multivariate analysis shows that N stage (HR, 3.427; 95% CI, 1.658-7.080; p = 0.001), M stage (HR, 3.940; 95% CI, 2.589-5.996; p <0.001), G grade (HR, 2.395; 95% CI, 1.565-3.666; p <0.001), pathological stage (HR, 3.003; 95% CI, 1.880-4.799; p <0.001) and DAPK1 expression (HR, 0.615; 95% CI, 0.422-0.896; p = 0.011) are independent prognostic factors that can predict DFS of ccRCC patients (Table 2).