ROC curve analysis was performed to evaluate the diagnostic significance of DAPK1 in ccRCC patients and showed that DAPK1 mRNA levels accurately distinguish ccRCC tissues from adjacent normal kidney tissue samples (AUC=0.6602; 95% CI: 0.6056-0.7148; p < 0.0001; Figure 3A). The gene discussed is DAPK1; the disease is nonpapillary renal cell carcinoma.