MAPK3 and neuroblastoma: Following its isolation from parental compound, the GM1-oligosaccharide added to the culture medium of N2a neuroblastoma cells was observed to induce the neuritogenesis process as equimolar concentration of GM1 did, acting at the PM level by enhancing the phosphorylation of the TrkA receptor followed by the increase in ERK1/2 phosphorylation [13].