Variants at many other loci like CAT (encodes catalase to detoxify hydrogen peroxide [H2O2]),15 IFIH1 (functions as pattern recognition receptor to activate innate immune response),16 and GZMB (encodes granzyme B to mediate cytotoxic T cell‐induced apoptosis)17 also confer increased predisposition to vitiligo onset. This evidence concerns the gene CAT and vitiligo.