We and others have implicated the transcription factor Stat3 in the progression of cachexia in several experimental models, including the C26 allograft, C26 LM and Apcmin/ + CRC models, as well as the Lewis Lung Carcinoma, B16 melanoma, and ES‐2 ovarian cancer models.46, 47, 48, 49, 50, 51, 52, 53, 54, 55. The gene discussed is STAT3; the disease is ovarian cancer.