ELAVL1 and amyotrophic lateral sclerosis: Among the RBP family, HuR is involved in the maintenance of inflammation and in the proper functioning of the immune system by positively regulating the stability of many target mRNAs, such as proinflammatory cytokines [12, 13], and recent findings described the role of HuR in defining the phenotype of activated microglia in amyotrophic lateral sclerosis [14].