CD40LG and dengue disease: IL-10 (p = 0.007), MIP-3α (p = 0.006) and IL-6 (p = 0.008) were significantly higher in patients who developed DHF during early illness (Fig. 5a–c) compared to those who developed DF, whereas sCD40L was higher in those with DF (p = 0.007) (Fig. 5d).