Nevertheless, microcephaly, seizures, growth retardation, hypotonia, and genitourinary abnormalities were reported in patients carrying missense mutations within the gene encoding the 60S ribosomal protein L10 (RPL10)51,52 and mild microcephaly, hearing loss, and dysmorphism was reported in patients with de novo mutations in RPS23 encoding ribosomal protein uS1253. The gene discussed is RPL10; the disease is microcephaly.