EGFR and neoplasm: Patients whose tumours harboured EGFR-amplification (ddPCR CNV score ≥2) had a median PFS of 4.57 months (95% CI 2.5 to 10.56 months), compared with 6.41 months (95% CI 5.99 to 7.34 months) for non-amplified cases (HR 1.30 (95% CI 0.78 to 2.16); p=0.32); a similar trend was observed when a higher threshold (ddPCR CNV score ≥5) was used for identifying EGFR-amplification (HR 1.70 (95% CI 0.92 to 3.12) p:0.09) (online supplemental table 5).