EGFR and neoplasm: EGFR CNV FISH data on chemonaïve pretreatment tissue (resections or biopsies) were available in 114 out of 200 patients enrolled in the phase II portion of the REAL3 trial; reasons for no availability of results included: (1) lack of patient consent for analysis (n=10); (2) insufficient tumour tissue left following previous analyses (n=36); (3) technical failure (n=18); (4) other reasons for example, block returned to treating hospital (n=22).