KRAS and neoplasm: Future studies using targeted approaches such as nanoString nCounter technology or low-pass WGS might further classify patients into three categories: (1) those whose tumours do not harbour coamplifications and are more likely to benefit from EGFRi; (2) those that carry targetable coamplifications that can be therapeutically exploited in anti-EGFR drug combinations; (3) those with undruggable coamplifications such those in EGFR and KRAS that are less likely to benefit from EGFRi alone.