GAD2 and cervical squamous intraepithelial neoplasia: As expected, CIN-relevant genes (e.g., Dlx1, Dlx2, Gad1, and Gad2) had significant enrichment of H3K27ac (greater activation) and depletion of H3K27me3 (less repression) in CINs compared with non-CINs (Figs. 1B, 2A; Extended Data Fig. 2-1B).