TCF7L2 and type 2 diabetes mellitus: Furthermore, among the DMRs which showed significant P values in a combined analysis but did not withstand adjustment for multiple testing (N = 661), we identified mostly new candidate genes but also confirmed genetic risk loci for BMI (N = 256), waist-to-hip ratio (N = 154), waist-circumference (N = 55), and type 2 diabetes (N = 130), such as the Transcription Factor 7-Like 2 (TCF7L2) (Additional file 2: Table S4, risk loci according to the GWAS catalog data accessed 04/2020) [37].