AFP and neoplasm: However, the results of the multivariate analysis suggested that only AFP (HR 1.566; CI 1.101–2.226; p = 0.013), PLR (HR 1.004; CI 1.001–1.007; p = 0.010), largest tumor size (HR 1.084; CI 1.027–1.145; p = 0.003), MVI (HR 2.509; CI 1.751–3.594; p<0.001) and Rad-score (HR 1.398; CI 1.188–1.646; p<0.001) were independently associated with an unfavorable postoperative survival.