To confirm that OTUD7B inhibits LCL161-induced lung cancer cell metastasis in vivo, we stably transfected empty vector, HA-OTUD7B(WT) and HA-OTUD7B(CH) plasmids into H1299 cells (Fig. 7a) and implanted the cells into nude mice via caudal vein injection. Here, OTUD7B is linked to lung carcinoma.