We did not observe differences in the incidence of different types of GC and EGJC, percentages of patients with high and low expression of HER2 protein, percentages of patients with high and low numbers of HER2 gene copies in liquid biopsy in groups of patients with or without HER2 gene amplification in tumor nuclei visualized by FISH method (chi square test, Table 3). This evidence concerns the gene ERBB2 and gastric cancer.