They identified several glycoproteins with elevated N-glycosylation levels correlated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3) and galectin-3-binding protein (LGALS3BP), which were involved in several well-known pancreatic cancer pathways such as: TGF-β, TNF, NF-kappa-B and TFEB related lysosomal changes [123]. This evidence concerns the gene TNF and familial pancreatic carcinoma.