After inhibiting PARP-1, CLytA-DAAO-induced cell death decreased in all the pancreatic and colorectal carcinoma cell lines tested, with the exception of the IMIM-PC-2 pancreatic carcinoma cell line (Figure 2), suggesting that PARP-1 plays a role in CLytA-DAAO-induced cell death in most of the cell lines tested. Here, PARP1 is linked to colorectal carcinoma.