Low-density lipoprotein (LDL) has attracted tremendous attention for its applications in cargo loading and delivery, owing to its unique features: LDL, as the major ligand for the low-density lipoprotein receptors (LDLR) that are highly expressed in quickly proliferating cells, allows moderate uptake of the drug in normally proliferating cells, and a highly increased uptake in cancer, a feature that potentially makes it an ideal carrier for PPs, which were shown in the literature to have beneficial antioxidant effects in low, and pro-oxidative and cytostatic effects in higher doses [4,5,6]. The gene discussed is LDLR; the disease is cancer.