HMGCR and myopathy: A subtype of IMNM is anti-HMGCR myopathy [101]; most patients with anti-HMGCR myopathy have a history or statin exposure, develop muscle weakness with highly elevated CK levels that persist despite statin cessation, are identified by the presence of circulating anti-HMGCR autoantibodies that can be directly pathogenic, and normally require treatment with immunosuppressive drugs or intravenous immunoglobulins [102].