NFE2L2 and neurodegenerative disease: In addition to dimethyl fumarate, Nrf2 activators such as curcumin, resveratrol, sulforaphane, masatinib, methylene blue, omaveloxolone, tideglusib, Dl-3-n-butylphthalide ide, ALKS-8700, benfotiamine, and ketogenic diet undergoing clinical trials for treating various neurodegenerative disease such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Friedreich’s ataxia, multiple sclerosis, amyotrophic lateral sclerosis, cataract, schizophrenia, bipolar disorder, mild cognitive impairment, depression, autism, obstructive sleep apnea, etc. [59].