CD4 and renal cell carcinoma: When testing for potential differences in reactivity among pairs tested separately with Young TILs (Y TILs) and Rapidly Expanded TILs (REP TILs) (Tables S2 and S3), no significant differences were observed in CD8+ (n = 132; 59 MM, 28 RCC and 45 OC; p = 0.25, Figure S1C) or CD4+ (n = 128; 55 MM, 28 RCC and 45 OC; p = 0.66, Figure S1D) T cell reactivity.