In order to assess whether the differences in the proportion of tumor-reactive CD8+ TILs observed in distinct tumor types were associated with other parameters of importance for T cell-mediated recognition of tumor-antigens, we re-analyzed data from The Cancer Genome Atlas (TCGA) and compared TCR richness [23] and antigen processing and presentation (APM) machinery activity across tumor types. Here, CD8A is linked to neoplasm.