CD86 and gastric cancer: In the present study, we employed the use of dendritic cell markers suitable for immunohistochemical analysis as previously reported [11] to visualize tumor-associated dendritic cells (TA-DCs) and bridge findings from the flow cytometry analysis of gastric cancer-derived exosomes with those of the immunohistochemical analysis of gastric cancer tissues; the dendritic cell markers we used include CD1a, which is a marker for immature monocyte-derived DCs (moDCs), CD83 and CD86 for mature or activated DCs [12], and other markers (S100, Langerin, and BDCA-2).