CRP and Sepsis: Furthermore, in our ongoing network meta-analysis, we found that CD64 displays a comparable sensitivity of 0.87 and superior specificity of 0.99 (95% CI: 0.81.0.92 and 0.92–1.00), among seven biomarkers (procalcitonin, CRP, IL-6, presepsin, CD64, sTREM-1, and lipopolysaccharide-binding protein), with respect to detecting systemic infection and sepsis, according to the Sepsis-3 definition [22].